Monday, 03 September 2007 23:41
New Gene for Height Discovered
According to the London Times a newly discovered
gene may be the common gene that influences height. The identification of this
gene is helping to explain why some people grow taller than others. People who inherit a
particular version of the gene, known as HMGA2, are on average a centimeter
taller than those who have a different genetic profile, scientists have
found.
It has long been established that stature is
heavily affected by a person’s genetic inheritance, which accounts for about 90
percent of the variation in height between people who have similar diets. While the effect of HMGA2 is
small, and tens if not hundreds of other genes are also involved in height, it
is the first common gene shown to have a direct link. Very rare mutations that
cause growth disorders have been pin-pointed before, but not genes that
influence normal variation.The gene was found by the same British team that
discovered FTO, the first common gene known to contribute to obesity. Just as
FTO is not a “fat gene”, HMGA2 is just one of many biological factors that affect
height. It would not be possible to guarantee having a tall child by screening
embryos for those with the “tall” variant, the scientists said.